James M. Sinclair, M.D.

I enjoy the complexity of oncology and hematology and the opportunity to care for patients and families at a most vulnerable time.

Dr. Sinclair


Internal Medicine

Medical Oncology


Hospice & Palliative Care


Education: University of Wisconsin-Madison

Residency: University of California, San Diego


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For Dr. Sinclair’s current patients:Who Do I Call?

About Dr. James Sinclair

Dr. Sinclair was raised in Wisconsin where he completed his undergraduate and medical school training at the University of Wisconsin-Madison. His mentor at Madison, Dr. Robert Schilling, suggested he do his post-M.D. training at UCSD with Dr. Helen Rainey and Dr. Mark Green, who continued to mentor him in the field of hematology and medical oncology. Dr. Sinclair began his private practice in 1987 and has spent the last several years fully engaged in the practice of hematology and medical oncology.

Dr. Sinclair is an optimistic and compassionate doctor. When treating patients, he first gains clinical insight and then creates a treatment plan based on each patient’s unique needs. Dr. Sinclair believes that the best way to support a patient is to help him or her maintain a great quality of life through a healthy diet, physical activity and stress management.

Dr. Sinclair has an office in La Jolla. He is the medical director of the Scripps Cancer Center at Scripps Memorial Hospital La Jolla. His interests include benign hematology, all forms of cancer and palliative medicine, which led to his position as medical director of a local hospice program. As a lover of sports, Dr. Sinclair sees himself as the “quarterback” for his patients as they try to navigate their way through the complex arena of cancer care.

In his spare time, Dr. Sinclair enjoys being outdoors hiking or hanging out at the beach. Dr. Sinclair enjoys craft beer and fine wine with his wife, and visiting his children and grandchildren.


Dr. Sinclair belongs to the American Medical Society, the American Society of Clinical Oncology, and the American Academy of Hospice and Palliative Medicine.

San Diego Magazine’s Top Doctor 2016 award recipient for Medical Oncology


Encinitas Mindfulness Community

Dr. Sinclair is part of the Encinitas Mindfulness Community, which practices meditation and compassionate action. He has found that mindfulness is an excellent tool for stress reduction, helping the mind and body heal.

“There is something almost magical about the ability to be mindful, to be awake,” says Dr. Sinclair. “I felt a connection not only to my loved ones, but to my patients and their families.”


“When I was told I had 3-5 years to live, I was scared, I was only 28 and having to face my own mortality … Twenty year olds aren’t supposed to have to deal with that … I’ve been seeing Dr. Sinclair for 24 years, and have the best doctor/medical team one could ask for!
– Chris Kimura, patient

Groundbreaking treatment from Dr. Sinclair

“Everyone from front staff to the techs, the nurses, practitioners and Dr. Sinclair are so very courteous, caring and responsive. Despite the fact that this is not a pleasant process to have to go through they all make me feel safe, well informed and important. I couldn’t ask for a better team!”

– Karen