Edward F. McClay, M.D.

In order to beat cancer, we must treat more than the disease itself. We must treat the whole person by being responsive to how cancer impacts all aspects of their lives.

Edward F. McClay, M.D. - Medical Oncology | cCARE, San Diego


Medical Oncology



Education: Temple University School of Medicine

Residency: Thomas Jefferson University Hospital

Fellowship: Thomas Jefferson University Hospital


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About Dr. Edward McClay

Dr. McClay received his B.A. and M.D. degrees from Temple University in Philadelphia, completing his medical residency and fellowship in medical oncology at Thomas Jefferson University. He spent 26 years at various universities achieving a rank of clinical professor of medicine.

Much of his career has been spent conducting melanoma research, and in 2015 he was recognized by Newsweek Magazine as one of their “Top Doctors” for melanoma and brain cancer treatments. Dr. McClay also treats patients with other malignancies and has been recognized as one of “America’s Top Doctors for Cancer” from 2013 through 2020 by the prestigious Castle Connolly Medical Group.

Dr. McClay continues his special interests in malignant melanoma and brain tumors. He co-authored the book “100 Questions and Answers about Malignant Melanoma and other Skin Cancers” with his wife, Mary-Eileen. They have been married for over 49 years and have two children.

Board certifications

  • Medical Oncology
  • Hematology


  • Castle Connolly America’s Top Doctors (2009, 2013-2020)
  • Castle Connolly America’s Top Doctors for Cancer (2009, 2014-2017)
  • Castle Connolly Top Doctors (2012-2013)

Doctor’s Blog

Read blog posts written by Dr. McClay.


“We have been in treatment for more than two years and things are improving all the time! Starting with Taylor and AJ, they make us feel cared for and like family. This is scary stuff and they smooth out the rough spots in many ways. Give them a raise! Nurse Jane has saved us so many times when Jim was doing poorly. She is spectacular! Vanessa and Monica have gone out of their way to help us. We are grateful for all the great care provided here. Dr. McClay saved Jim’s life. If your diagnosis is metastatic melanoma, you are in he best of all possible hands!”

– Jim and Anita Brusso